New Findings in Veterinary Microbiology

New Findings in Veterinary Microbiology

Antibiotic resistance survey of Klebsiella pneumonia isolates collected from clinical specimens in Khatam (PBUH) Hospital, Zahedan

Document Type : Original Article

Authors
Bahman Hormozi
Mahboubeh Barekzaei
Zahra Rasheki Ghalehnoo
10.35066/J040.2018.192
Abstract
Klebsiella pneumoniae is the one of UTI bacteria and relevant opportunistic pathogen that causes nosocomial infections. Antibiotic resistance of the Klebsiella species is increasing nowadays; therefore, antibiogram test is necessary before prescribing antibiotics. This research is aimed to determine the rate of antibiotics resistance of Klebsiella pneumoniae isolated from clinical specimens of patients referred to Khatam hospital during September 2013 to May 2014 using Kirby-Bauer method. This descriptive and analytic surveywas performed on 83 isolates of Klebsiella pneumonia collected from Khatam hospital. After phenotypical and biochemicalidentification of isolate, drug resistance was investigated for 10 antibiotics through the standard CLSI procedure via the Kirby-Bauer method. The percentage of resistance to all of the isolates of Klebsiela pneumonia were Cefexime 82%٫ Cefotaxime 81%٫ Ceftriaxone 73%٫ Ceftazidime 72%٫ Amikacin 63%٫ Azithromycin 60%٫ Tetracycline and Nalidixic Acid 59%٫ Gentamicin 58% and Imipenem 43%. The results indicated that the lowest resistance percent was for Imipenem in all tested Klebsiella; therefore, it can be recommended as the most effective antibiotic for Klebsiella isolates in study area.
Keywords
Disk diffusion
Zahedan
Klebsiella pneumonia
Antibiotics resistance
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New Findings in Veterinary Microbiology
Volume 1, Issue 2
April 2019
Pages 82-88

  • Receive Date 08 January 2018
  • Revise Date 04 February 2018
  • Accept Date 12 March 2018