Detection of Leptospirosis Bacteria in Rodent Urine Using Metamaterial Absorber Based Surface Plasmon Resonance (SPR) Sensor

Document Type : Original Article

Authors

1 Assistant Professor, Department of Physics, Faculty of Science, University of Zabol, Zabol, Iran

2 Assistant Professor, Department of Electrical Engineering, Faculty of Engineering, University of Zabol, Zabol, Iran

Abstract

Leptospirosis is a common disease between humans and animals that can survive in swimming pools, rivers, surface waters, moist soils, swamps, and hot weather. Leptospirosis can be transmitted to humans directly through contact with the urine of most rodents (rats, foxes, raccoons, etc.) by scratches or minor injuries, or indirectly through contaminated water and soil. Considering that the cultivation and growth of this bacterium is time-consuming, the use of surface plasmon resonance sensors using metamaterial structure is a suitable method for rapid diagnosis of this disease. Ordinary, leptospirosis bacteria can be detected by urine. In this article, we apply five rodent urine samples as the sensing material in the designed biosensor. In the proposed structure, gold metal has been chosen as a plasmonic metal due to its resistant against air oxidation. To check the sensitivity of this device and the results, we find absorption curves and analyze them in terms of sensitivity, detection accuracy, and quality factor. The results show that this sensor can detect leptospirosis bacteria with a sensitivity of 1315nm/RIU and a figure of merit (FOM) of 63RIU-1.

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References

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New Findings in Veterinary Microbiology
Volume 6, Issue 1
September 2023
Pages 13-20

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History

  • Receive Date: 13 December 2022
  • Accept Date: 19 April 2023

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