The Comparative survey of clinical effects of two commercials Marbofloxacin on E.coli clinical mastitis in Holstein dairy cows

Document Type : Original Article

Authors

1 Head of Dept. if Theriogenology, Faculty of Vet. Med. Univ. of Tehran. Tehran-Iran.

2 Section of Theriogenology, Department of Clinical Sciences, Faculty of Veterinary Medicine, Ferdowsi University of mashhad.

3 The retired professor of department of surgery, Faculty of Veterinary Medicine, University of Tehran.

10.35066/J040.2018.625

Abstract

Environmental mastitis has been increased significantly in recent years due to control of contagious mastitis agents. Marbofloxacin is an antibiotic which is the derivatives of Carboxylic acid, the third generation of Fluoroquinolone. It has antibacterial activity against gram negative and positive bacterial. The aim of this study was the comparative effects of two injectable solutions of Marbofloxacin manufactured by 2 European companies on environmental mastitis due to E. Coli.
Milk samples were taken from 86 with clinical mastitis dairy cows and cultured. Fifty cows contaminated with E.coli and treated after diagnosis. Animals stratified to two groups, treatment and control. The treatment group animals (N. 25) were taken injectable antibiotic solution of Marbofloxacin manufactured by a Belgian company, 2mg/Kg, (1ml/50Kg body weight) IM for 3 days. The control group animals (N.= 25) were taken injectable antibiotic solution of Marbofloxacin manufactured by a French company 2mg/Kg, (1ml/50Kg body weight) IM for 3 days. The animals in treatment and control groups were cured 40% and 53%, respectively. There were no significant differences using chi-square statistical method (P>0.05).
It is concluded that Marbofloxacincan of both companies are affected on mastitis due to E.Coli.

Keywords

References

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New Findings in Veterinary Microbiology
Volume 1, Issue 2
April 2019
Pages 76-81

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History

  • Receive Date: 10 February 2019
  • Revise Date: 02 March 2019
  • Accept Date: 11 March 2019

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