Document Type: Original Article
university of Zabol
This study aimed to evaluate the antibacterial and antifungal activity of various extracts of the Rhazya stricta, Capparis spinosa, cretica Cressa. Rhazya stricta, Capparis spinosa, cretica Cressa plant collected from Saravan city, Sistan and Balouchestan Province. Extraction with different solvents was performed with a rotary machine. Standard bacteria were purchased from Persian Type Culture Collection (PTCC). Minimum inhibitory concentration and minimum bactericidal concentration were determined by the micro-dilution method. The results of this study showed that the lowest inhibitory concentration of the aqueous extract against E. coli, Bacillus cereus, and Shigella dysenteriae was 2.5 mg/ml. The results of this study also showed that the lowest inhibitory concentration was related to methanolic extracts of Cressa, which is equal to 0.62 mg/ml and Bacillus cereus bacterium is inhibited in this concentration. The lowest inhibitory concentration of the Caper extract (0.62 mg/ml) that inhibited Escherichia coli and Bacillus cereus, belonged to ethanolic extract. Also in the same concentration, the hydroalcoholic and methanolic extracts inhibited Shigella disneraceae and Pseudomonas aeruginosa. The results of this study indicate that the extract of the Cressa and Caper herb has good antimicrobial effects on fungal and bacteria pathogenesis.