بررسی اثر تجویز داخل رحمی عصاره آویشن در گاوهای مبتلا به آندومتریت بالینی بر میزان وقوع سقط در آبستنی متعاقب

نوع مقاله : مقاله پژوهشی

نویسنده

استادیار گروه علوم درمانگاهی، دانشکده دامپزشکی، دانشگاه تبریز، تبریز، ایران

چکیده

اندومتریت یکی از رایج‌ترین بیماری‌ها و عفونت‌های رحمی بعد از زایمان است که عوامل باکتریایی مختلفی از جمله تروپرلا پایوژنز، اشریشیاکلی، فوزوباکتریوم نکروفروم و پری‌وتلا ملانینوجنیکوس در پاتوژنز این بیماری نقش دارند. از داروی گیاهی آویشن به دلیل خواص ضد باکتریایی در درمان اندومتریت گاو استفاده شده است اما احتمال می‌رود دارای اثرات جانبی روی جنین باشد. هدف از مطالعه‌ی حاضر بررسی اثرات سقط‌زایی عصاره آویشن است که برای درمان گاوهای مبتلا به آندومتریت قبل از شروع آبستنی انفوزیون داخل رحمی شده است. تعداد 48 رأس گاو شیری آبستن با سابقه اندومتریت بالینی که به دنبال انفوزیون داخل رحمی پلاسیبو (تعداد=6)، پنی‌سیلین+استرپتومایسین (تعداد=19) و عصاره آویشن (تعداد= 23) بهبود یافته و آبستن شده بودند وارد این مطالعه گردیدند. ارزیابی آبستنی در گروه‌های درمانی از 30 روزگی آبستنی تا زمان زایمان گاوها از راه اولتراسونوگرافی راست روده‌ای انجام شد. موارد سقط جنین در هر گروه ثبت گردید. آنالیز آماری داده‌های مطالعه حاضر با استفاده از نرم‌افزار آماری  SPSSبا سطح معناداری 05/0 ≥P انجام شد. نتایج این مطالعه نشان داد که در گروه عصاره آویشن میزان سقط‌زایی (8/34 درصد) در مقایسه با گروه کنترل (صفر درصد) و گروه درمانی پنی‌سیلین+استرپتومایسین (5/10 درصد) بیشتر بود، که این تفاوت از لحاظ آماری به شدت نزدیک به معناداری بود (06/0 =P). با توجه به نتایج مطالعه حاضر انفوزیون داخل رحمی عصاره آویشن در گاوهای شیری می‌تواند رخداد سقط را افزایش دهد، لذا درمصرف آویشن بهتر است احتیاط بیشتری صورت گیرد.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of intrauterine administration of Zataria multiflora ex-tract in cows with clinical endometritis on the incidence of abortion in subsequent pregnancy

نویسنده [English]

  • abolfazl hajibemani
1 - Assistant Professor, Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tabriz, Tabriz, Iran
چکیده [English]

Endometritis is one of the most common uterine diseases postpartum. Arcanobacterium pyogenes, Escherichia coli, Fusobacterium necrophorum and Prevotella melaninogenicus bacteria are that correlated with endometritis. Zataria (Z) multiflora extract has antibacterial effect that has been used for treatment of endometritis in cows. But it may have adverse effects on the fetus. The objective of the present study was to determine the abortion effects of Z multiflora extract in pregnant cows that improved from endometritis before pregnancy using Z multiflora extract. 48 pregnant dairy cows with a history of clinical endometritis that improved and became pregnant following intrauterine infusion of placebo (n = 6), penicillin + streptomycin (n = 19) and Z multiflora extract (n = 23) were included in this study. Evaluation of pregnancy of treatment groups was performed using ultrasonography from 30 days of gestation to calving. Abortions were recorded in treatment groups. The data was statistically analyzed using the SPSS software .values of p≤ 0.05 was considered as significant data. The results of this study showed that the percentage of abortion was higher in Z. multiflora extract group(34.8%) compared to the control group (0%) and the penicillin + streptomycin group (10.5%), This difference was statistically very close to significant (P = 0.06). According to the results of the present study, intrauterine infusion of Z. multifloracan can increase the incidence of abortion in dairy cows, so it is to be more cautious in consuming of Z. multiflora.

کلیدواژه‌ها [English]

  • Words:Abortion
  • Endometritis
  • Cow
  • Z. multiflora
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